CONTACT INFO :: EDUCATION :: APPOINTMENTS :: SURGICAL EDUCATION :: PEER REVIEWED PUBLICATIONS

INFORMATION - Andrew W. Knott

Andrew W. Knott, M.D.

OFFICE ADDRESS:
North Alabama Vascular Consultants, PC
One Hospital Drive
Crestwood Medical Pavilion
Building 2
Suite 300 (directions)
Huntsville, AL 35801

TELEPHONE:
256-885-4333 (OFFICE)
256-885-3733 (FAX)

EMAIL:
knott.andrew@northalabamavascular.com

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Additional Information i.e.(Patient info, Our Services,
News, etc.) - Click Here - TVVC.org

EDUCATION, CERTIFICATIONS & LICENSES

EDUCATION:
M.D., University of South Alabama 1999
College of Medicine
Mobile, Alabama

B.S., Biology 1993
Summa Cum Laude
Freed-Hardeman University
Henderson, Tennessee

RESIDENCY:
Department of Surgery 1999-2006
University Hospital
University of Cincinnati

FELLOWSHIP:
Vascular Surgery 2006-Present
Mayo Clinic
Rochester, Minnesota

CERTIFICATION:
Basic Life Support (BLS) 1999-Present

Advanced Cardiac Life Support (ACLS) 1999-Present

Advanced Trauma Life Support (ATLS) 2000-2006

American Board of Surgery 2006-Present

MEDICAL LICENSE:
Alabama 2008-Present

Minnesota 2006-Present

South Dakota 2006-Present

APPOINTMENTS

Crestwood Medical Center 2008-Present
Huntsville, Alabama

Huntsville Hospital 2008-Present
Huntsville, Alabama

HealthSouth Rehabilitation Hospital 2008-Present
Huntsville, Alabama

SURGICAL EDUCATION

RESEARCH EXPERIENCE:
Research Fellow, NIH Trauma Training Grant 2001-2003
Principal Investigators: Joseph Solomkin, M.D.
and Brad Warner, M.D.
Department of Surgery
University of Cincinnati

Research Fellow 2001-Present
Principal Investigator: Brad Warner, M.D.
Division of Pediatric Surgery
Department of Surgery
University of Cincinnati

Student Fellow 1995
University of South Alabama
College of Medicine
Principal Investigator: James Hunter, M.D.
Department of Structural and Cellular Biology

Research Assistant 1993-1994
University of Louisville
Principal Investigator: Michael Edwards, M.D.
Department of Surgery
Division of Surgical Oncology

PEER REVIEWED PUBLICATIONS

1. Knott AW, Cassivi S, Gloviczki P. Open Central Venous Reconstruction: Technique, Advantages, and Pitfalls of Partial Sternotomy With Infraclavicular Resection of the First Rib. Persp Vasc Endovasc Surg (In Press)

2. Knott AW, Kalra M, Duncan AA, Reed NR, Bower TC, Hoskin TL, Oderich GS, Gloviczki P. Open repair of juxtarenal aortic aneurysms (JAA) remains a safe option in the era of fenestrated endografts. J Vasc Surg. 2008 Feb 11 (Epub ahead of print)

3. Jarboe MD, Juno RJ, Bernal NP, Knott AW, Zhang Y, Erwin CR, Warner BW. Bax deficiency rescues resection-induced enterocyte apoptosis in mice with perturbed EGF receptor function. Surgery. 2004 Aug; 136(2):121-6.

4. Juno RJ, Knott AW, Jarboe MD, Profitt SA, Erwin CR, Warner BW. Characterization of small bowel resection and intestinal adaptation in germ-free rats. Surgery. 2003 Oct;134(4):582-9; discussion 589-90.

5. Knott AW, Juno RJ, Jarboe MD, Profitt SA, Erwin CR, Smith EP, Fagin JA, Warner BW. Smooth muscle overexpression of IGF-I induces a novel adaptive response to small bowel resection. American Journal of Physiology Gastrointestinal Liver Physiology. 2004 Sep;287(3): G562-70. Epub 2004 May 13.

6. Juno RJ, Knott AW, Profitt SA, Jarboe MD, Zhang Y, Erwin CR, Warner BW. Preventing enterocyte apoptosis after massive small bowel resection does not enhance adaptation of the intestinal mucosa. Journal of Pediatric Surgery. 2004 Jun;39(6):907-11.

7. Knott AW, O'Brien DP, Juno RJ, Zhang Y, Williams JL, Erwin CR, Warner BW. Enterocyte apoptosis after massive small bowel resection in mice is activated independent of the extrinsic death receptor pathway. American Journal of Physiology Gastrointestinal Liver Physiology. 2003 Aug;285(2):G404-13.

8. Juno R, Knott AW, Racadio J, Warner B. Reoperative venous access. Seminars in Pediatric Surgery. 2003 May; 12(2): 132-9.

9. Juno R, Knott AW, Erwin C, Warner B. A serum factor(s) after small bowel resection induces intestinal epithelial cell proliferation: effects of timing, site, and extent of resection. Journal of Pediatric Surgery. 2003 Jun; 38(6): 868-874.

10. Knott AW, Juno R, Jarboe M, Zhang Y, Profitt S, Thoerner J, Erwin C, Warner B. EGF receptor signaling affects Bcl-2 family gene expression after massive small bowel resection. Journal of Pediatric Surgery. 2003 Jun; 38(6): 875-880.

11. Knott AW, Juno R, Williams J, Erwin C, Warner B. Epidermal growth factor receptor (EGFR) signaling regulates the expression of P21WAF1 after small bowel resection (SBR). Journal of the American College of Surgeons. September 2002; Volume 195(3) Supplement: S10.

12. Knott AW, Juno RJ, Erwin CR, Warner BW. Laser-capture microdissection to localize EGFR expression after small bowel resection in mice. Journal of Pediatric Surgery. March 2003; Volume 38(3): 440-445.

13. Juno RJ, Williams J, Knott AW, Erwin CR, O'Brien DP, Warner BW. A serum factor after intestinal resection stimulates EGFR signaling and proliferation in intestinal epithelial cells. Surgery August 2002; 132(2): 377-83. 14. Knott AW, Ampudia RJ, Evankovich C, Teplick SK, Herrera JL, Tucker JA Jr, Rodning CB. Biliary cystadenoma: rare variant of intrahepatic cystic disease. Southern Medical Journal. 93(7): 698-702, 2000 July.

15. Nakagawa K, Miller FN, Knott AW, Edwards MJ. Pentoxifylline inhibits N-formyl-Methionyl-Leukocyl-Phenylalanine-induced macromolecular leakage. American Journal of Physiology. 269: H239-H245, 1995 July.

16. Anderson JA, Woodcock TM, Harty JI, Knott AW, Edwards MJ. The effects of oral pentoxifylline on interleukin-2 toxicity in patients with metastatic renal cell carcinoma. European Journal of Cancer. 31A(5): 714-7, 1995.

17. Anderson JA, Knott AW, Sims DE, Edwards MJ. The effect of soluble tumor necrosis factor receptor-II on endotoxin-mediated hemodynamic instability in the rat. Journal of Surgical Research. 58(1): 53-7, 1995 Jan.

BOOK CHAPTERS AND ELECTRONIC PUBLICATIONS
1. Knott AW. Gastric Tumors. Mont Reid Surgical Handbook, Fifth Edition.

2. Knott AW. Peptic Ulcer Disease. Mont Reid Surgical Handbook, Fifth Edition.

3. Knott AW and Johannigman JA. Tracheostomy and Percutaneous Enteral Feeding Tubes. In: Farmer JC, Wall MH, eds. Pocket ICU Management. New York: PocketMedicine.com, Inc., 2003.

ABSTRACTS
1. Knott AW, Kalra M, Duncan AA, Reed NR, Bower TC, Hoskin TL, Oderich GS, Gloviczki P. Open repair of juxtarenal aortic aneurysms (JAA) remains a safe option in the era of fenestrated endografts. Midwestern Vascular Surgical Society Meeting, September 6-8, 2007, Chicago, IL.

2. Knott AW, Duncan AA, Hanna AM, Bjarnason H, Bower TC, McBane RD, Gloviczki P. Subclavian Venous Effort Thrombosis in Adolescents: Preventing Long-Term Disability. 19th Annual American Venous Forum, February 14-18, 2007, San Diego, CA.

3. Robb B, O'Brien D, Knott AW, Rafferty J. Anal melanoma: A case report and review of the literature. Annual Meeting of the Ohio Valley Society of Colon and Rectal Surgeons. Columbus, Ohio, April 24, 2004.

4. Knott AW, Selwyn C, Gersin K. Predictors of early discharge after laparoscopic Roux-en-Y gastric bypass. Annual Meeting of the Society of American Gastrointestinal Endoscopic Surgeons. Denver, Colorado, April 1-4, 2004.

5. Jarboe M, Juno R, Stehr W, Knott AW, Bernal N, Profitt S, Erwin C, Warner B. Alterations in small intestinal secretory lineages after small bowel resection. Presented at the Annual Meeting of the Society of University Surgeons. St. Louis, Missouri, February 2004.

6. Juno R, Knott AW, Profitt S, Jarboe M, Zhang Y, Erwin C, Warner B. Preventing enterocyte apoptosis after massive small bowel resection does not enhance adaptation of the intestinal mucosa. The National Conference and Exhibition of the American Academy of Pediatrics, New Orleans, Louisiana, November 1-5, 2003.

7. Juno RJ, Knott AW, Jarboe, M., Erwin, C., Warner, B. P21 is elevated and intestinal adaptation is preserved in P27-Null mice following small bowel resection. Accepted for poster presentation at Digestive Diseases Week 2003, American Gastroenterological Association, Orlando, FL, May 17-22, 2003.

8. Knott AW, Juno RJ, Jarboe MD, Erwin CR, Smith EP, Fagin JA, and Warner BW. Smooth muscle overexpression of IGF-I results in a novel adaptive response to small bowel resection. Accepted for poster presentation at DDW 2003, American Gastroenterological Association, Orlando, FL, May 17-22, 2003.

9. Juno RJ, Knott AW, Jarobe MD, Profitt SA, Erwin CR, and Warner BW. Characterization of small bowel resection and intestinal adaptation in germ free rats. Accepted for presentation at the Central Surgical Association, Toronto, Ontario, March 20-22, 20 03.

10. Knott AW, Juno RJ, Jarboe MD, Erwin CR, and Warner BW. Compensatory ileal expression of p27kip1 after massive small bowel resection in p21waf1-null mice. Presented at the Association for Academic Surgeons, Boston, MA, November 5-10, 2002.

11. Juno RJ, Knott AW, Erwin CR, and Warner BW. A serum factor(s) after small bowel resection induces intestinal epithelial cell proliferation: effects of timing, site, and extent of resection. Presented at the American Academy of Pediatrics, Section of Pediatric Surgery, Boston, MA, October 18-23, 2002.

12. Knott AW, Juno RJ, Williams JL, Erwin CR, and Warner BW. Defective epidermal growth factor receptor (EGFR) signaling affects bcl-w gene expression after massive small bowel resection (SBR). Presented at the American Academy of Pediatrics, Section of Pediatric Surgery, Boston, MA, October 18-23, 2002.

13. Knott AW, Juno RJ, Williams JL, Erwin CR, and Warner BW. Epidermal growth factor receptor (EGFR) signaling regulates the expression of p21waf1 after small bowel resection (SBR). Presented at the Surgical Forum, 88th Annual Clinical Congress, American College of Surgeons, San Francisco, CA, October 6-10, 2002.

14. Juno RJ, Williams J, Knott AW, Erwin CR, O'Brien DP, and Warner BW: A serum factor after intestinal resection stimulates EGFR signaling and proliferation in intestinal epithelial cells. Presented at the annual meeting of the Society of University Surgeons, Honolulu, Hawaii, February 13-16, 2002.

15. Knott AW, Juno RJ, Erwin CR, and Warner BW. Laser capture microdissection to localize EGFR expression after small bowel resection in mice. Presented at the annual meeting of the American Pediatric Surgical Association, Phoenix, Arizona, May 19-22, 2002.

16. Anderson JA, Knott AW, Wilson MA, Garrison RN, Edwards MJ. Soluble tumor necrosis factor receptor-I, but not soluble tumor necrosis factor-II, abrogates endotoxin-mediated hemodynamic instability. Presented at the Eighteenth Scientific Symposium of the Association of VA Surgeons.

17. Harty JI, Anderson JA, Woodcock TM, Knott AW, Edwards MJ. The impact of oral pentoxifylline on interleukin-2 toxicity for the treatment of metastatic renal cell carcinoma. Presented at the annual meeting of the Irish Society of Urology, Charlemont Clinic, Dublin, Ireland, April 23, 1994.